Description
DESCRIPTION
Restylane Refyne is specially developed for soft, flexible correction of moderate facial lines, particularly in high-movement regions such as the perioral area. Using XpresHAn Technology, Restylane Refyne combines elasticity and subtle support, allowing the filler to adapt smoothly to facial expressions. This makes it ideal for patients who want to diminish wrinkles without compromising natural movement or experiencing a “frozen” appearance. Its gel structure mimics the skin’s natural flexibility while maintaining enough cohesiveness for reliable wrinkle reduction.
Restylane Refyne also contains lidocaine, an anesthetic that helps relieve pain during the procedure. It integrates into the skin to help smooth out lines that appear alongside the corners of the mouth and restores skin elasticity for a natural-looking facial appearance and expressions. Also, clinicians prefer Restylane Refyne for its versatility and ease of placement in dynamic wrinkles such as nasolabial folds and marionette lines. Its moderate viscosity allows refined smoothing while maintaining softness. Patients benefit from refreshed, youthful contours that look organic, not overcorrected. Restylane Refyne’s combination of flexibility, durability, and minimal post-treatment swelling makes it an excellent option for first-time filler patients or those wanting subtle, expressive rejuvenation.
STRENGTHS OF RESTYLANE REFYNE
- Treats superficial to deep facial lines such as nasolabial folds and marionette lines.
- Created by a unique technology to balance the elasticity and support of the facial features
- Exceptional flexibility for natural facial expression
- Contains lidocaine to help relieve discomfort in the target area during the treatment
- Soft correction for moderate wrinkles
- Smooth, adaptable gel texture
- Reduced swelling and downtime
- Clinically proven long-lasting integration
SCOPE OF APPLICATION
Restylane Refyne is used for:
- Nasolabial folds
- Marionette lines
- Perioral wrinkles
- Light secondary cheek rejuvenation
- Facial lines and wrinkles
- Perioral lines
- Moderate smile lines
DURATION OF EFFECT
Restylane Refyne produces effects that last up to 9–12 months. Results can be prolonged with maintenance treatment sessions that can be done regularly, with a duration that must be decided by a medical professional.
PRODUCT COMPOSITION
Restylane Refyne contains the following ingredients:
- Hyaluronic Acid (20 mg/mL)
- Lidocaine (0.3%)
- Phosphate-buffered solution
PRODUCT INFORMATION OF RESTYLANE REFYNE
Packaging: 1 x 1.0 mL pre-filled syringes per box
Composition: 20 mg/mL Cross-linked Hyaluronic acid and 3 mg/mL lidocaine
Indications: Facial lines and wrinkles, moderate to severe nasolabial folds, marionette lines, perioral lines, smile lines
Injection depth: Mid- to deep-dermal layer
Needle size: 30G
Method of administration: Applicable for use with manual injection (micro-bolus, serial puncture, or linear threading)
Recommended dosage: Injection volume to achieve optimal correction of moderate to severe nasolabial folds is generally about 1.5 mL per treatment site. The injection volume to achieve optimal correction for retreatment is generally about 1.0 mL per treatment site.
Treatment protocol: The interval in getting Restylane Refyne varies depending on one’s individual metabolism and the amount of product used. It will also depend on the doctor’s evaluation.
Aftercare Instructions: Avoid exposure to extreme temperatures like heat, such as heat, sunbathing, saunas, and steam baths, and cold until signs of inflammation have disappeared. The patient must not apply any creams or cosmetics in the treated area before the skin has healed completely to prevent infections or inflammatory reactions.
Duration of effect: 12 months
Shelf life: 36 months from the manufacturing date.
Storage: Store the product in a cool and dry place (between 2°C and 25°C). Protect from sunlight and freezing temperatures.
Manufacturer: Galderma Laboratories
**It is recommended that a medical professional be the only one to administer Restylane Refyne to prevent untoward side effects and maximize the outcomes of the product.




