Description
PRODUCT DESCRIPTION
Bienox is a Korean-made botulinum toxin type A neuromodulator designed to provide consistent, natural wrinkle relaxation and precise muscle attenuation. Bienox is manufactured by BNC Korea under GMP and ISO-certified sterile conditions, providing aestheticians with a stable, consistent toxin suitable for a wide range of facial rejuvenation procedures. Its formulation includes a high-purity neurotoxic compound stabilized by human albumin and sodium chloride.
Bienox acts by temporarily inhibiting acetylcholine transmission at the neuromuscular junction. This reduces excessive muscle contractions and allows dynamic wrinkles, such as frown lines, crow’s feet, and forehead creases, to gradually smooth out, giving the patient a refreshed, youthful appearance. Bienox’s controlled diffusion profile delivers subtle but effective softening without making the treated area appear stiff or over-frozen. The product is intended to be simple to reconstitute, easy to inject, and predictable in clinical behavior, making it convenient for both novice injectors and experienced aesthetic practitioners.
STRENGTHS OF BIENOX
- It is formulated with high-purity Clostridium Botulinum Toxin, with constant potency when administered, yielding expected outcomes.
- It has a smooth, balanced diffusion for natural aesthetic results.
- The toxin rapidly dissolves, making it easier for simple handling, resulting in clinical efficiency
- Ideal for full-face treatment for muscle spasms and wrinkle preventative therapies.
- Reliable onset and duration, equivalent to general Korean neurotoxins in the market
- Safe and well-tolerated, with minimal immunogenicity and side effects.
SCOPE OF APPLICATION
It is important to note that Bienox should only be administered by a healthcare practitioner with appropriate qualifications and expertise.
- Glabellar frown lines
- Forehead lines
- Crow’s feet
- Nasal bunny lines
- Perioral wrinkles and lip flip enhancement
- Chin dimpling
- Eyebrow shaping
- Masseter reduction for jawline contouring
- Neck rejuvenation (platysmal bands)
DURATION OF EFFECT
Bienox produces its initial effect within 3 to 7 days. The effects reach their peak after 10 to 14 days. The duration lasts around 3 to 4 months. However, the results may differ for each individual depending on various factors.
PRODUCT COMPOSITION
Bienox comes in a lyophilized powder form containing the following ingredients:
- Clostridium botulinum toxin type A strain – 100U
- Human serum albumin – 0.5 mg
- Sodium chloride – 0.9 mg
BIENOX PRODUCT INFORMATION
Packaging: 100U x 1 vial. Each package may contain one vial or 10 vials.
Product appearance: A white or light-yellow lyophilisate contained in a colorless and transparent vial. When reconstituted with saline, Metox appears as a transparent solution.
Injection depth: Intramuscular or intradermal injection
Needle size: 29 – 30G
Reconstitution: Mix Bienox vial with 0.9% sterile saline solution before administering the product.
Recommended usage: The amount of Metox to be used will depend on the target area and the medical professional’s discretion after a thorough evaluation of the face.
Treatment interval: Intervals between treatments should not be shorter than 3 months.
Duration of effect: 3-4 months
Storage: Store the product in a refrigerator (2°C-8°C). To prevent bacterial contamination, the interior of the fridge should be kept sterile and the vials clean. After reconstitution, store Metox in the refrigerator for 24 hours.
Shelf-life: 24 months from the date of manufacture
Manufacturer: BNC Korea
**Bienox is recommended for medical professionals and licensed aestheticians for use only. This is to prevent adverse reactions and maximize the effectiveness of Bienox.




