Description
PRODUCT DESCRIPTION
Demei cross-linked hyaluronic acid fillers can be used to meet each patient’s cosmetic needs and come in a variety of viscoelastic gel types. With cutting-edge technology and facilities from DKBIO Co., Ltd. and EG DONG AN Aesthetic Clinic Network, the Demei Dermal Filler product line is a masterpiece that has been given a personal touch. The development of Demei Cross-Linked Hyaluronic Acid Fillers centers on its potential to restore youthfulness from the inside out and from the outside. It is manufactured using premium raw materials, and the hyaluronic acid has been approved as a monophasic gel type that is safe and contains few cross-linking agents (BDDE). Because DKBIO uses safe manufacturing techniques to produce the Demei Fillers, it has received approval from various regulatory bodies, including the USFDA and the European Directorate for the Quality of Medicines (EDQM).
The LEDM Method, also known as the Low-chemical & Enhanced Double Cross-linking Method, is a proprietary process used to produce the hyaluronic acid formulation of Demei Cross-Linked Hyaluronic Acid Fillers. By employing prolonged, low-temperature procedures, this method reduces the portion of incomplete cross-linking in the hyaluronic acid gel and increases the rate of complete cross-linking. In addition to the cross-linking technology, Demei Fillers’ hyaluronic acid undergoes a purification process known as ATER, or Advanced Technique for Elimination of Residues, which uses minimal BDDE to achieve the total removal of residual toxins through repeated cleaning. Demei Cross-Linked Hyaluronic Acid Fillers, a soft-type gel filler that promises ideal volume and natural outcomes, have exceptional viscoelasticity and are made of excellent HA particles. Demei fillers’ qualities enable them to effectively treat aging symptoms such as wrinkles and facial lines, sagging skin, acne scars, hyperpigmentation, and compromised skin barrier.
STRENGTHS OF DEMEI CROSS-LINKED HYALURONIC ACID FILLERS
- Uses a small amount of BDDE agents to provide the hyaluronic acid particles with a complete cross-linking rate.
- Produces minimal to no adverse side effects, thus making the product safe to administer according to EDQM and US FDA regulations.
- Demei Cross-Linked Hyaluronic Acid Fillers have soft viscoelastic qualities and a consistent cross-linked HA structure that creates natural volume.
- Offers easy molding, smooth injection sensation, and a variety of application options.
- Provides long-lasting results due to its cohesiveness, maintaining its stable structure without migrating to other surrounding tissues after administration.
- Fills in wrinkles on the forehead, including deep glabellar frown lines, nasolabial folds, and improves uneven skin texture.
- Contours and defines the cheeks and nose bridge as well as overall facial volume, creating a youthful appearance.
- Aging lines and wrinkles on the face and neck can be readily treated with it.
- Serves as a perfect non-surgical alternative, especially for augmentation procedures
- Results are noticeable right away with no downtime needed.
SCOPE OF DEMEI CROSS-LINKED HYALURONIC ACID FILLERS
- Fine facial lines
- Lip contour
- Under-eye rejuvenation
- Marionette lines
- Facial wrinkles and folds
- Deep forehead wrinkles
- Glabellar frown lines
- Chin augmentation
- Cheek augmentation
- Nose bridge and tip contouring
- Nasolabial folds
- Face V-line shaping
DURATION OF EFFECT
Demei Cross-Linked Hyaluronic Acid Fillers may last from 3 to 12 months, depending on the type of filler used. The duration of effect will also depend on the patient’s condition and the doctor’s technique.
PRODUCT COMPOSITION
For Demei Cross-Linked Hyaluronic Acid Fillers, all of the fillers in the product line contain 20mg/mL hyaluronic acid.
DEMEI CROSS-LINKED HYALURONIC ACID FILLERS PRODUCT INFORMATION
PRODUCT RANGE
DEMEI #1

Packaging: 1 x 1.0 mL pre-filled syringe with 2 sterile needles
Composition: 20mg/mL Hyaluronic acid
Gel type: Moderate viscosity, good elasticity, and cohesiveness
Injection Depth: Superficial dermal layer
Needle size: 30G x ½ “ (13mm)
Indications: Correct superficial and light wrinkles and fine lines in the face and neck.
Application: Fine facial lines, lips, and around the eyes
Duration of effect: 3 – 6 months
Storage: Store the product at room temperature (1°C to 30°C). Do not freeze or heat the product. Keep away from direct sunlight. Do not put any force or pressure on the product.
Shelf life: 24 months
Manufacturer: DKBio Co., Ltd
DEMEI #2

Packaging: 1 x 1.0 mL pre-filled syringe with 2 sterile needles
Composition: 20mg/mL Hyaluronic acid
Gel type: Highly viscous, good elasticity, and moderate cohesiveness
Injection Depth: Superficial dermal layer
Needle size: 27G x ½ “(13mm)
Indications: Correction and improvement of moderate wrinkles, lines in the face and neck. Subtle contouring of the face and lips
Application: Marionette lines and moderate facial wrinkles and folds
Duration of effect: 10 – 12 months
Storage: Store the product at room temperature (1°C to 30°C). Do not freeze or heat the product. Keep away from direct sunlight. Do not put any force or pressure on the product.
Shelf life: 24 months
Manufacturer: DKBio Co., Ltd
DEMEI #3

Packaging: 1 x 1.0 mL pre-filled syringe with 2 sterile needles
Composition: 20mg/mL Hyaluronic acid
Gel type: High elasticity and cohesiveness, with moderate viscosity
Injection Depth: Deep dermis layer, subcutaneous tissue
Needle size: 27G x ½ “(13mm)
Indications: Filling deep and stubborn wrinkles and folds. This is for augmentation, contouring, and face volumizing.
Application: Forehead, chin, and cheek augmentation, nose contouring, nasolabial folds, and face line shaping
Duration of effect: 10 – 12 months
Storage: Store the product at room temperature (1°C to 30°C). Do not freeze or heat the product. Keep away from direct sunlight. Do not put any force or pressure on the product.
Shelf life: 24 months
Manufacturer: DKBio Co., Ltd
**Demei Cross-Linked Hyaluronic Acid Fillers must be administered by a medical professional or dermatologist to prevent untoward reactions.




